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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f40d9078f9be8268324ec930558dbdbd01538fb0e405a3c666557baa0ca8c5f1' 
  AND token = 'OnUB1bY8iUw9/8EwOKEgCxNE9XsIH1kIQJnAC5vJP7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}