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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef067696f8cdd3b6c77c8a44ab5dadbb8a18e1886d4b761ab91d31bfedb91f52' 
  AND token = '43Z+08h5ikMcIv+nE+WhiRz/ZeoN/fCGTNGDq3ELiwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}