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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16ca8d2609052b5a5b22fc5b0f33d1c57071a47d4f8e4c52afd5a6fa1a07ebe5' 
  AND token = '1x/FPUY1qZH9rc6n/E06JjaPDSt1ELk9E3+8WjDCmRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}