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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb8a322fad9c6de84530cc7be908b8a037070631f3bb949da3fbec5cdd836378' 
  AND token = '5mrKasS+RS5J4Da3p2Y0l6096mdgCT3z6dbrpCKPGSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}