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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d141fac266099169234ea1eb8c01bc0dc9e43f2a5776ba414af5f3b48952978' 
  AND token = 'TBYONaxg6yDpJDAnR2sRKa2pzolJ+sDPbTriRtJCr2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}