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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99ecfb0d4c077feb0f0e7e3b08894f744e8bd2b9c6b6b7982c8dba242944c93f' 
  AND token = '1d8pCvDIOVaBP1DduLn0eV+u9cI7u4D4ZNmO9+tzbGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}