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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dbf2a078c0ee5c3ce53a2319fdf492b0d87495d1d79948e9ddd73d5eaad4604' 
  AND token = 'v+1jxnZF8XZEg3MD0EJMYapxyzeg5jod0Ps8kMbz49k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}