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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45bb7db07b50a049833a86a867ff777a2cf1e4e782ca5a16246053545fc0f085' 
  AND token = 'F2euTuSOs2ld5dbJ6yJlg1gUaBa8pb/n7NfxYQM+bY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}