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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '347ab9d51c1d4b0b71d3c8d4fb725b6816640046a44cf47adcee4b59b6343cad' 
  AND token = 'GSJXNELw+YpLBFw24c2aqDwQkU2l0vBqPVi42b2aNxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}