SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e482842e41a4b6952816271b375203d70f5ca44353866ddd3c2538bafc8fb4' 
  AND token = 'V8N9l6mRyw5adRH2MreDzsWMsWgVY+sK+P7Ip4/j0Gk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}