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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4de323feade83af3a9b5e2a4cc9b3709f04b5be81e1b76980812932f36275c0f' 
  AND token = 'LXe9qs7lG++mZPP0RyCyJ/6Wyo6E1aQTJQNuDHmhLkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}