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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09c6d21708c9364f583d9e0f22939e1a70e18c3b22659e4e4377ed12cdeaa313' 
  AND token = 'uOJQx7ySCDRD1r6BdQA2OGX3/TujhNUCOXP1OBWM0oM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}