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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bedbe21e33fc4fc33c84fc9b3ccc3a2c455b5f78a801e183e24b3484bc3dac0' 
  AND token = 'mTFqjk2A6GNn6SmEn6E5wZwxDyGZt8nR8SN4V+YWNqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}