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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25d78efc92048eff6069591d5a1298eefcfb45eb131495e2545896cf7053a5fa' 
  AND token = 'J6X6r0yPZCMAg9pLsx2b4e+kF0Z1XN8+FZHFnrycAQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}