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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89daf1917a58768062cf1da4412461c68225083b752c00a41557cf34147190c2' 
  AND token = 'VlMB1YSqj+ra/FMOLWSJuS0RlLEkXs0QrfjpY5JNHQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}