SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1841d1bca8bb1ad68abceaae5747f8f38b20faaf1e8f1247af6c75e2baae48b' 
  AND token = 'Mj2MQYxIHc8R+8GbUsNmIUDiG9VOU3z7CO/LAkACrJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}