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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26a18a8395f4656c35a28a523822707cb144a9520bc9fcf9d43ea0fe495bd242' 
  AND token = '/6/3XwMF1MuC002zip741PNgejzQVAO0SN1tGVAiA6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}