SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69a71a92b13da72e9fce7a52ce47dc83716faf4eb9782c863567d86a25b288bf' 
  AND token = 'wy8MkjC33/zYSoIztT+1T1Rmqx3VlUXAqSZFOEqdFwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}