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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9d8d03053f582cf8df28e71a3f3d475a4e46ac4addecc0b837f48b8bd09df55' 
  AND token = 'A5NtAntElNrDDqh+aA244GpZQdJRbM1j0E0CuwDYI4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}