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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d7670c75a913e3152fd5e8b234a0ae775580ebbabe1c38e7b353f2f0c28daae' 
  AND token = 'yObSwv2+sYEAr6Pf+V7V+ZdDVDSBc661lroMLaCWY4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}