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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4333ce4e4e41b968e5f8902b83be9d1927042b9549165a33b92f846b9d16ff38' 
  AND token = '5qT4bv2Aiaa/KmIuYAwXOeuzxLYVnDYVogAONuFjRk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}