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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e656bf5eb1ee25bd1eaca67646c3b4044ae4497b68ce1106b3daf21e2428553' 
  AND token = 'Crs8IDf1mOOaW/9ShQcQ1beyJpFg4CaPQ98y/zekcmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}