SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d3bbb693ef433ebb7cac1e6950bc09d485f7c53e507e31872e9f24c32d98073' 
  AND token = 'Szo7w0GLETqMUVYWxeyxqqbUqjzszGFgJwg8D5tLpEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}