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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c185c396fe47cb8733d0103a9b24687337da7fbcc3ffbbb61894eb7f0c27ce42' 
  AND token = 'LZohMDpSXlPHQVEHRRSJ8huqxcnt1MfKNz2IMz+tEt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}