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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c2c2f427f8b6172f316fc806cd3ef8f5c51daf188372f0c3d1fff1bc04c9651' 
  AND token = 'F2R+I32ylFs1xGCqbN/1H4/Ude7qlR/Ia9kF6lKBOpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}