SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48b9bc614a2bd2803b6b136a8e83f3de41bf068d67e29673a8dc6e4aa03a37f2' 
  AND token = 'ACWxOfu3aKGDoNxRoYS17qVT7rIWzOnwDUeTKmBLYTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}