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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53ef9c1d796c2d84aaab7d95d963dc8c4350469f819393ed91be7c012eae8a30' 
  AND token = 'jQG5f7NzGxoxu/eSZzUyTxKeIkNWILp8mTqrJPFmJ0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}