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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df2b9de3b6890abe9a279355be8b2268bd0b3a624a5d266f44809126e2703782' 
  AND token = 'kbt5wx41oTmnTgj5NrTtec3bTIJDR65jpuZwaEgxzsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}