SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '386b7364181775a196d661c4c99b33a9f1fd785f17a072f53f4486b9a2e16276' 
  AND token = 'uIMm/C5bxlCZzQTMZxnWf3+Z1rUrJ20q6duCT9TXS9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}