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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eaa4d2253cf0d212650e4b2912329b6018dfd5fa1b478ed0b8d03f39eaf78378' 
  AND token = 'IpbMqrM1YqI1F3BwPxLag0fqm25M4ez7Bmhu6SYG0Ms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}