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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da0ec456939042e87442fb1d42966b8ce579adb15eb59105237c9a9f05578bdc' 
  AND token = 'oM0u+2xIYjTlsU2E1MFEoMSAMtwfBnTprsL22PnOp5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}