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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b83856f15a1039c1ba55a771682a6bfb946e445a5615e44dd7ca58391649f4a' 
  AND token = 'xEVA4/taa8WKqMpduOtBX01ZZK7qCgDTDPRrSeM5oTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}