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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5fc7ace15200f9d9afbef55eb303b17dce929088fc5cd17c73dcdc23da01752' 
  AND token = 'sNi8/redX1CdFDoT6SkutVrs/p55H8moGJMQWu0M/Qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}