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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cbc1e6192e6eece94b97a41a5885f6a240b07b6d3f5695f7ea2681ae521c943' 
  AND token = 'oojto1CE/m7148AjRur9VDZPHNm3RrxEvm9bSSEySUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}