SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34cccd9371437c3fbd3b62a37fd21db227cc4ba904cb865409c6ed5f6774dce4' 
  AND token = 'NDjQ9C7ubSxG6TumlpR9jT0hWH+MbXmZjUBwBI61kWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}