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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '493020078adc98da573ae5691cf38b94a2797fd777f089b1cecd9655a6d5d02a' 
  AND token = 'UMNxeJc1AVXYA8GsGAVqKTi9mcXJHdO9wUtoHhfEwsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}