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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce1ffd9c6e688576ea6e17362307ed62b33a1e10b64986880117514ff8be957b' 
  AND token = 'vDG2/op/BB3H1X7ZRc8AfrRREK4yADKfSVwiNwtKvDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}