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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e65998eeb75c8df4f091609087254e5dc3ee1f92c08b0df7283e7338d8ba1ba3' 
  AND token = 'COYHEf5S4tZm0htma4pQyHpGVEQArC+bMmv0iSCSw8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}