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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9366686dece4e130a57776b2d5353ccb9e73d0bc693b0cf35ef7e01b351b2884' 
  AND token = 'NZlI9XLZT7ZAd2FHATcQYUKxcv+INSPD5R4eqK5Z9p4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}