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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6650531f1edf1337448c5a3c563e3f3f6c6671746d949e9ee800ce6c36620d12' 
  AND token = 'mOL7zmdwCCwBZSgcyel5f37wvfTWDLjV9921FCz5cNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}