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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54866f31ea802b9c491a765a244c9a651fffe03616cf4a22c9a045782bad8cc3' 
  AND token = 'TB4hHF4E0zQxb6FNs0sWNiymdWtqN8xwUseYtBMMtn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}