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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e57b94fb07ef6166a4253dcbb87c815f09c6b40c0ba7b3033935215cb9e4064f' 
  AND token = 'xw2mLETESAO9No3hyszp4wA72jByVqNEjWqk/Ep4UMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}