SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08f8aa00335afc26c383e713e2d773a75e021d6f0097e277b6752dbfcb204890' 
  AND token = 'Cf8ITIYPLlZof1VuNxumItdsQEnrG5nQ5hpvYavnuLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}