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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b7d4a5f6f5e18588f21cc9306a11284ead922cd1c5ea7e34281fe40cf713575' 
  AND token = 'U/Rt7+YJre0jk+3zlcoqwpzsFK1fJBdpCc9eZat1jxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}