SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c691fbe2d7a10edb1a475e5d7e3f5dd4b775b72dee934394d766544fbe3ee2f0' 
  AND token = 'dzI478v0Kqjf0nhsguiTzwgGKfv2BVbveLZoPizCMYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}