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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f0bd350b93969d94115a49d295d007d8f8eab7030901e3682246befd3b1a0fd' 
  AND token = 'RWG8PdGQ6fK5NtIqimIUvrfkXbwSdysYSt8nkLjfj5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}