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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6a0cbb294ec00ec515d2297c69bda3aa9ad6f2876124517ba686e6ecf6036c4' 
  AND token = 'YABuTrAPDg1EbHYFlWn0bBZvYc8JGnaxhSYuZAvGITw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00073

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}