SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '916253059f948ce139689088a43459f0462a509e28d53946584854307edd22d3' 
  AND token = 'U7F9yQ/mv9SFzoxJziKWrE/PKylKIF88kK8RKv9leeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}