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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e2264c708781df8cb975b4cd4b9966fc94a0f762c5a5392d16747fec1672c22' 
  AND token = 'm1Ev0V+7SfUybLRduh4CYTBkR66Fs+zAvgfgiE6CD9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}