SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f5cfa33405371845941b1df1da58b0df57deed058781b0ba677bc9a0ad2bf61' 
  AND token = 'PfKKgvxZQRAccTnwgio9PLZKLeIxeMYr7SS+d8bzw3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}